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Advancing In Vivo Gene Editing for Sickle Cell Disease and HIV

Tessera Therapeutics, a Cambridge, Massachusetts–based biotechnology company, is developing an in vivo gene editing platform using an all-RNA approach to target hematopoietic stem cells, with the goal of enabling direct, durable genetic modification without the need for ex vivo cell manipulation. The Foundation’s investment accelerates development of a Phase 1-ready sickle cell disease candidate and supports early-stage research in HIV.
Website
Focus areas
Life Sciences
Investment type
Direct equity
Status
Active
Initial investment
Convertible Note
Partnered in
2024
Headquarters
USA
Portfolio news
Tessera Therapeutics Receives Investment to Develop Curative In Vivo Genetic Treatment for Sickle Cell Disease

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We embrace science and technology innovations that solve old problems in new ways, challenge status quos, and build on past breakthroughs. Our six domains of focus comprise 40+ program strategies across the foundation’s nearly $9B annual charitable support.

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The SIF Investment Committee brings depth of experience to global investment programs, with a proven track record of innovation across sectors and scale.

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